| Gene Symbol | Full Name | Neurotrophic and/or protective activity | in vitro evidence (articles) | in vivo evidence (articles) | condition-specific effects (articles) | Supporting sentences (in vitro) | Supporting sentences (in vivo) | Supporting sentences (condition-specific) |
|---|---|---|---|---|---|---|---|---|
| BDNF | brain derived neurotrophic factor | neurotrophic/neuroprotective | DOI:10.1084/jem.189.5.865 DOI:10.1016/0896-6273(90)90166-D DOI:10.3858/emm.2010.42.8.060 DOI:10.1002/neu.480250805 |
DOI:10.1002/dev.20546 DOI:10.1242/dev.008227 DOI:10.1006/mcne.1998.0684 DOI:10.1016/0896-6273(93)90326-M DOI:10.1038/331261a0 DOI:10.1016/S0165-3806(98)00155-2 PMID:8656282 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 Supporting sentence 5 Supporting sentence 6 Supporting sentence 7 |
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| NGF | nerve growth factor | neurotrophic/neuroprotective | DOI:10.1126/science.3798108 DOI:10.3858/emm.2010.42.8.060:10.1038/jcbfm.1993.51 |
PMID: 10403429 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
||
| NTF3 | neurotrophin 3 | neurotrophic/neuroprotective | DOI:10.1016/j.neulet.2012.04.036 |
DOI:10.1038/367368a0 DOI:10.3727/096368909X477273 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 |
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| NTF4 | neurotrophin 4 | neurotrophic | DOI:10.1002/neu.480250805 |
PMID:8656282 |
Supporting sentence 1 |
Supporting sentence 1 |
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| GDNF | glial derived neurotrophic factor | neurotrophic/neuroprotective | DOI:10.1126/science.8493557 |
DOI:10.1016/S0165-3806(98)00155-2 DOI:10.1016/0361-9230(94)00224-O |
PMID:16838029 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
| FGF1 | fibroblast growth factor 1 | neurotrophic | PMID:1941074 DOI:10.1046/j.1471-4159.2002.00837.x |
Supporting sentence 1 Supporting sentence 2 |
||||
| EGF | epidermal growth factor | neurotrophic | DOI:10.1126/science.3498986 PMID:2406380 |
PMID:8076517 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
||
| IGF1 | insulin like growth factor 1 | neurotrophic | PMID:9030615 PMID:2406380 |
PMID:10632601 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
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| PDGFA | platelet-derived growth factor A | no trophic/protective activity identified | DOI:10.1007/BF00229041 |
|||||
| PDGFB | platelet-derived growth factor B | neurotrophic | PMID:1654560 DOI:10.1016/j.neuroscience.2004.11.056 DOI:10.1007/BF00229041 |
DOI:10.3727/096368909X477273 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 |
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| VEGFA | vascular endothelial growth factor | neurotrophic | DOI:10.1073/pnas.182296499 PMID:10407014 DOI:10.1046/j.0953-816X.2000.01326.x |
DOI:10.1073/pnas.182296499 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 |
||
| VEGFB | vascular endothelial growth factor | neurotrophic | DOI:10.1073/pnas.182296499 PMID:10407014 DOI:10.1046/j.0953-816X.2000.01326.x |
DOI:10.1073/pnas.182296499 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 |
||
| VEGFC | vascular endothelial growth factor | neurotrophic | DOI:10.1073/pnas.182296499 PMID:10407014 DOI:10.1046/j.0953-816X.2000.01326.x |
DOI:10.1073/pnas.182296499 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 |
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| VEGFD | vascular endothelial growth factor | neurotrophic | DOI:10.1073/pnas.182296499 PMID:10407014 DOI:10.1046/j.0953-816X.2000.01326.x |
DOI:10.1073/pnas.182296499 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 |
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| CDNF | cerebral dopamine neurotrophic factor | neurotrophic/neuroprotective | DOI:10.1016/j.bbrc.2013.04.029 |
DOI:10.1038/nature05957 DOI:10.1016/j.expneurol.2010.12.013 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 |
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| MANF | mesencephalic astrocyte derived neurotrophic factor | neurotrophic | DOI:10.1385/JMN:20:2:173 |
DOI:10.1002/cne.22039 DOI:10.1523/JNEUROSCI.0833-09.2009 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 |
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| NENF | neudesin neurotrophic factor | neurotrophic | DOI:10.1002/jnr.20356 DOI:10.1002/jnr.20849 |
DOI:10.1074/jbc.M706679200 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
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| ARTN | artemin | neurotrophic | DOI:10.1016/S0896-6273(00)80649-2 |
DOI:10.1006/mcne.1999.0817 |
Supporting sentence 1 |
Supporting sentence 1 |
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| NRTN | neurturin | neurotrophic | DOI:10.1006/mcne.1999.0756 |
DOI:10.1006/exnr.1999.7175 |
Supporting sentence 1 |
Supporting sentence 1 |
||
| PSPN | persephin | neurotrophic | DOI:10.1016/S0896-6273(00)80453-5 |
DOI:10.1016/S0896-6273(00)80453-5 |
Supporting sentence 1 |
Supporting sentence 1 |
||
| HGF | hepatocyte growth factor | neurotrophic/neuroprotective | DOI:10.1046/j.1471-4159.2002.00837.x DOI:10.1097/00004647-199804000-00001 |
PMID:11509947 |
DOI:10.1046/j.1471-4159.2002.00837.x |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
Supporting sentence 1 |
| ADNP | activity-dependent neuroprotector homeobox | neurotrophic/neuroprotective | DOI:10.1016/j.mce.2006.03.029 |
DOI:10.1124/jpet.107.129551 |
Supporting sentence 1 |
Supporting sentence 1 |
||
| METRNL | meteorin, glial cell differentiation regulator-like | neurotrophic/neuroprotective | DOI:10.1038/sj.emboj.7600202 PMID:22044868 DOI:10.1242/jcs.063784 |
PMID:22044868 DOI:10.3233/RNN-2012-110199 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 Supporting sentence 2 |
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| MDK | Midkine (Neurite Growth-Promoting Factor 2) | neurotrophic/neuroprotective | DOI:10.1016/0304-3940(93)90904-Y PMID:8827451 |
DOI:10.1186/1471-2202-11-42 DOI:10.1038/sj.gt.3302434 |
DOI: |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 Supporting sentence 2 |
|
| CHRNA7 | cholinergic receptor nicotinic alpha 7 subunit | neurotrophic/neuroprotective | PMID:28890319 PMID:17493709 |
PMID:22624500 |
DOI:10.1016/j.neuropharm.2013.10.034 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
Supporting sentence 1 |
| PINK1 | PTEN induced putative kinase 1 | neurotrophic/neuroprotective | PMID:25611391 |
Supporting sentence 1 |
||||
| BAG1 | BCL2 associated athanogene 1 | neurotrophic/neuroprotective | PMID:20156966 PMID:19712056 |
Supporting sentence 1 Supporting sentence 2 |
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| STAT3 | signal transducer and activator of transcription 3 | no trophic/protective activity identified | ||||||
| AQP4 | aquaporin 4 | neurotrophic/neuroprotective | PMID:27057365 PMID:26433375 |
PMID:28714415 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
||
| FOXO3 | forkhead box O3 | no trophic/protective activity identified | ||||||
| SHH | sonic hedgehog | neurotrophic/neuroprotective | PMID:9221786 |
PMID:11771942 |
Supporting sentence 1 |
Supporting sentence 1 |
||
| TRPM2 | transient receptor potential cation channel subfamily M member 2 | no trophic/protective activity identified | PMID:27872485 PMID:21383889 |
Supporting sentence 1 Supporting sentence 2 |
||||
| TTR | transthyretin | neurotrophic/neuroprotective | PMID:21880910 |
PMID:27518433 |
Supporting sentence 1 |
Supporting sentence 1 |
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| SLPI | secretory leukocyte peptidase inhibitor | neurotrophic/neuroprotective | PMID:23516280 PMID:20047904 |
Supporting sentence 1 Supporting sentence 2 |
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| SAG | S-antigen visual arrestin | no trophic/protective activity identified | ||||||
| TRH | thyrotropin releasing hormone | neurotrophic/neuroprotective | PMID:24199031 |
Supporting sentence 1 |
||||
| AVP | arginine vasopressin | neurotrophic/neuroprotective | PMID:15266902 |
Supporting sentence 1 |
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| AIDA | axin interactor, dorsalization associated | no trophic/protective activity identified | ||||||
| LBP | lipopolysaccharide binding protein | no trophic/protective activity identified | ||||||
| CAST | calpastatin | neurotrophic/neuroprotective | PMID:22897874 PMID:21219955 |
PMID:22843411 PMID:16467455 PMID:12764095 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
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| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | neurotrophic/neuroprotective | PMID:27254664 |
PMID:20857515 PMID:22027994 PMID:27254664 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
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| AK7 | adenylate kinase 7 | no trophic/protective activity identified | ||||||
| HTRA2 | HtrA serine peptidase 2 | neurotrophic/neuroprotective | PMID:14534547 PMID:15509788 |
Supporting sentence 1 Supporting sentence 2 |
||||
| AGTR2 | angiotensin II receptor type 2 | neurotrophic/neuroprotective | PMID:23174180 |
PMID:19246705 PMID:24849663 PMID:23174180 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
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| APP | amyloid beta precursor protei | neurotrophic | PMID:29478851 PMID:29426354 |
PMID:29478851 PMID:29426354 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 Supporting sentence 2 |
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| VGF | VGF nerve growth factor inducible | neurotrophic | PMID:28287464 |
Supporting sentence 1 |
||||
| ADAM10 | ADAM metallopeptidase domain 10 | neurotrophic/neuroprotective | PMID:10097139 PMID:20676056 |
PMID:15146243 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
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| GALR2 | galanin receptor 2 | neurotrophic/neuroprotective | PMID:16487144 PMID:15041741 PMID:19717462 PMID:22624057 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 |
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| SIRT1 | sirtuin 1 | neurotrophic/neuroprotective | PMID:23293585 PMID:22179319 DOI:10.1155/2017/2823454 |
PMID:22179319 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 |
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| CX3CR1 | C-X3-C motif chemokine receptor 1 | neurotrophic/neuroprotective | PMID:16732273 PMID:22072684 |
PMID:22072684 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
||
| SIRT2 | sirtuin 2 | no trophic/protective activity identified | PMID:17588900 PMID:29654491 PMID:25608039 |
PMID:17588900 PMID:29654491 PMID:16732273 PMID:22072684 PMID:25461978 PMID:25608039 |
PMID:25608039 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 Supporting sentence 5 Supporting sentence 6 |
Supporting sentence 1 |
| XBP1 | X-box binding protein 1 | neurotrophic/neuroprotective | PMID:29518365 PMID:28487326 PMID:17890727 PMID:27646263 PMID:28726788 |
PMID:28726788 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 Supporting sentence 5 |
Supporting sentence 1 |
||
| CRH | corticotropin releasing hormone | neurotrophic/neuroprotective | PMID:12933679 |
PMID:23380766 PMID:18708129 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 |
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| MT3 | metallothionein 3 | neurotrophic/neuroprotective | DOI:10.1016/S0304-4165(02)00325-2 DOI:10.1080/09553000050051025 DOI:10.1016/S0006-8993(03)02633-7 DOI:10.1006/bbrc.2001.4594 DOI:10.1016/j.molbrainres.2004.09.011 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 Supporting sentence 5 |
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| CXCR4 | C-X-C motif chemokine receptor 4 | neurotrophic/neuroprotective | DOI:10.1016/j.jns.2012.01.001 DOI:10.1002/ana.21919 |
Supporting sentence 1 Supporting sentence 2 |
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| CPE | carboxypeptidase E | neurotrophic/neuroprotective | PMID:18570185 PMID:18550819 DOI:10.1210/en.2013-1118 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
||||
| KDR | kinase insert domain receptor | no trophic/protective activity identified | ||||||
| OPTN | optineurin | no trophic/protective activity identified | DOI:10.1038/eye.2011.309 |
Supporting sentence 1 |
||||
| TIMP3 | TIMP metallopeptidase inhibitor 3 | neurotrophic/neuroprotective | PMID:26299440 |
PMID:26299440 |
Supporting sentence 1 |
Supporting sentence 1 |
||
| YY1 | YY1 transcription factor | no trophic/protective activity identified | ||||||
| PTHLH | parathyroid hormone like hormone | neurotrophic/neuroprotective | DOI:10.1074/jbc.272.22.14404 DOI:10.1016/S0006-8993(01)03407-2 |
DOI:10.1016/S0006-8993(01)03407-2 DOI:10.1152/ajpregu.00436.2002 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 Supporting sentence 2 |
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| GAP43 | growth associated protein 43 | neurotrophic/neuroprotective | DOI:10.1038/cdd.2008.188 DOI:10.1002/(SICI)1097-4547(19970315)47:6<561::AID-JNR1>3.0.CO |
Supporting sentence 1 Supporting sentence 2 |
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| NTRK3 | neurotrophic receptor tyrosine kinase 3 | neurotrophic | DOI:10.1038/nrd4024 |
Supporting sentence 1 |
||||
| FGF9 | fibroblast growth factor 9 | neurotrophic/neuroprotective | DOI:10.1111/j.1471-4159.2009.06061.x DOI:10.1016/j.freeradbiomed.2010.06.026 DOI:10.1016/S1044-7431(03)00070-8 |
DOI:10.1111/j.1471-4159.2009.06061.x |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 |
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| PRL | prolactin | neurotrophic | DOI:10.1016/j.neuroscience.2006.12.053 |
PMID:21507086 |
Supporting sentence 1 |
Supporting sentence 1 |
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| SORT1 | sortilin 1 | neurotrophic | DOI:10.1016/j.tins.2012.03.007 |
DOI:10.1038/nn.2689 |
Supporting sentence 1 |
Supporting sentence 1 |
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| NLK | nemo like kinase | no trophic/protective activity identified | DOI:10.1007/s12031-013-0191-5 PMID:19840224 DOI:10.1371/journal.pone.0069148 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
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| CARTPT | CART prepropeptide | neurotrophic | DOI:10.1016/j.bbrc.2006.06.117 |
PMID:21756347 |
Supporting sentence 1 |
Supporting sentence 1 |
||
| GJA1 | gap junction protein alpha 1 | no trophic/protective activity identified | ||||||
| CALCA | calcitonin related polypeptide alpha | no trophic/protective activity identified | ||||||
| GRN | granulin precursor | neurotrophic/neuroprotective | PMID:18378771 PMID:21820214 PMID:21204008 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
||||
| ALS2 | ALS2, alsin Rho guanine nucleotide exchange factor | neurotrophic/neuroprotective | PMID:16049005 PMID:16802292 |
PMID:16107644 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
||
| EP300 | E1A binding protein p300 | neurotrophic | PMID:21705428 PMID:27256286 |
PMID:23804093 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
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| NGB | neuroglobin | neurotrophic/neuroprotective | PMID:25023896 PMID:21915648 |
PMID:22167093 PMID:22703519 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 Supporting sentence 2 |
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| ADCYAP1 | adenylate cyclase activating polypeptide 1 | neurotrophic/neuroprotective | PMID:16805827 PMID:16004991 PMID:21524257 |
PMID:15084446 PMID:15518897 PMID:21524257 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
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| ATG12 | autophagy related 12 | no trophic/protective activity identified | ||||||
| ADORA1 | adenosine A1 receptor | neurotrophic/neuroprotective | PMID:9221954 |
Supporting sentence 1 |
||||
| NPAS4 | neuronal PAS domain protein 4 | neurotrophic/neuroprotective | PMID:26661154 PMID:24887558 |
PMID:26661154 PMID:26661154 PMID:24887558 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
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| INS | insulin | neurotrophic/neuroprotective | DOI:10.1016/j.jalz.2013.05.1140 PMID:3045261 PMID:12808000 |
PMID:19203442 |
PMID:10690636 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 |
Supporting sentence 1 |
| SYT10 | synaptotagmin 10 | neurotrophic/neuroprotective | PMID:26936998 |
Supporting sentence 1 |
||||
| PHB | prohibitin | no trophic/protective activity identified | ||||||
| NTRK1 | neurotrophic receptor tyrosine kinase 1 | neurotrophic | PMID:11756477 |
Supporting sentence 1 |
||||
| DUSP6 | dual specificity phosphatase 6 | neurotrophic/neuroprotective | PMID:15530650 |
Supporting sentence 1 |
||||
| XG | Xg blood group | no trophic/protective activity identified | ||||||
| TERT | telomerase reverse transcriptase | neurotrophic/neuroprotective | PMID:25632141 PMID:23968592 PMID:10854254 |
PMID:25632141 PMID:27974126 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 Supporting sentence 2 |
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| TES | testin LIM domain protein | no trophic/protective activity identified | ||||||
| CGA | glycoprotein hormones, alpha polypeptide | neurotrophic/neuroprotective | DOI:10.5665/sleep.5148 |
Supporting sentence 1 |
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| DAP | death associated protein | no trophic/protective activity identified | ||||||
| PTH | parathyroid hormone | no trophic/protective activity identified | ||||||
| S100B | S100 calcium binding protein B | neurotrophic | PMID:22489319 PMID:15584905 PMID:17639288 PMID:26899964 |
PMID:20728493 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 |
Supporting sentence 1 |
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| FGF20 | fibroblast growth factor 20 | neurotrophic/neuroprotective | PMID:22971544 |
Supporting sentence 1 |
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| PSAP | prosaposin | neurotrophic | PMID:18481277 |
Supporting sentence 1 |
||||
| PTN | pleiotrophin | neurotrophic/neuroprotective | PMID:27468976 |
PMID:22008908 PMID:27468976 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 |
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| HDGF | heparin binding growth factor | neurotrophic/neuroprotective | PMID:22531700 |
Supporting sentence 1 |
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| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase | no trophic/protective activity identified | ||||||
| HTT | huntingtin | neurotrophic/neuroprotective | DOI:11278258 |
DOI:12062094 DOI:16452687 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 |
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| GRIN2A | glutamate ionotropic receptor NMDA type subunit 2A | no trophic/protective activity identified | ||||||
| GRIN2B | glutamate ionotropic receptor NMDA type subunit 2B | no trophic/protective activity identified | ||||||
| TXN | thioredoxin | neurotrophic/neuroprotective | DOI:20298786 DOI:10.1074/jbc.M110701200 DOI:10.1093/abbs/37.2.119 |
DOI:19940280 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 |
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| ENO2 | enolase 2 | neurotrophic/neuroprotective | DOI:10.1016/0168-0102(94)00849-B DOI:22257123 DOI:23621429 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
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| SEMA4D | semaphorin 4D | no trophic/protective activity identified | ||||||
| NRN1 | neuritin 1 | neurotrophic/neuroprotective | DOI:10.1038/cddis.2015.22 DOI:10.1038/cddis.2014.478 DOI:15606892 DOI:10.1007/s11064-018-2553-4 |
DOI:29334295 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 |
Supporting sentence 1 |
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| FLT3LG | fms related tyrosine kinase 3 ligand | neurotrophic | DOI:10.1006/mcne.2001.1033 |
Supporting sentence 1 |
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| GNRH1 | gonadotropin releasing hormone 1 | neurotrophic | DOI:10.15406/mojap.2016.02.00063 |
Supporting sentence 1 |
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| NR4A2 | nuclear receptor subfamily 4 group A member 2 | neurotrophic/neuroprotective | PMID:28348207 DOI:27940361 |
PMID:28348207 PMID:27940361 |
PMID:26383113 PMID:26124091 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 Supporting sentence 2 |
| PARK7 | Parkinsonism associated deglycase | neurotrophic/neuroprotective | PMID:28165637 |
PMID:16860563 PMID:18003894 |
PMID:19276614 PMID:20087465 PMID:22041943 PMID:21372141 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 |
| HDAC7 | histone deacetylase 7 | neurotrophic | PMID:30018556 |
Supporting sentence 1 |
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| UCP2 | uncoupling protein 2 | neurotrophic/neuroprotective | PMID:12960023 |
PMID:24965893 PMID:22266335 PMID:18018477 |
PMID:24670857 PMID:19356683 |
Supporting sentence 1 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 Supporting sentence 2 |
| CBL | Cbl proto-oncogene | no trophic/protective activity identified | ||||||
| MIA | melanoma inhibitory activity | no trophic/protective activity identified | DOI: |
DOI: |
Supporting sentence 1 |
Supporting sentence 1 |
Supporting sentence 1 |
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| TH | tyrosine hydroxylase | no trophic/protective activity identified | ||||||
| THOP1 | thimet oligopeptidase 1 | neurotrophic/neuroprotective | PMID:18571100 |
Supporting sentence 1 |
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| CRLF3 | cytokine receptor like factor 3 | no trophic/protective activity identified | ||||||
| ATF3 | activating transcription factor 3 | no trophic/protective activity identified | PMID:18194435 |
Supporting sentence 1 |
||||
| HDAC4 | histone deacetylase 4 | neurotrophic | PMID:23480850 PMID:23349832 |
PMID:27660204 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
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| NPY | neuropeptide Y | neurotrophic/neuroprotective | PMID:26311075 PMID:23358924 PMID:18412629 PMID:17212973 |
DOI:22537092 PMID:21816512 PMID:19318226 PMID:19176820 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 |
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| GPNMB | glycoprotein nmb | neurotrophic/neuroprotective | PMID:22891158 PMID:29519253 |
PMID:25010402 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
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| SIRT3 | sirtuin 3 | neurotrophic/neuroprotective | PMID:23139766 PMID:25452082 PMID:29567426 PMID:28197079 |
PMID:26058697 PMID:26698917 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 Supporting sentence 4 |
Supporting sentence 1 Supporting sentence 2 |
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| SOCS1 | suppressor of cytokine signaling 1 | no trophic/protective activity identified | ||||||
| GDF15 | growth differentiation factor 15 | neurotrophic/neuroprotective | PMID:11102463 |
Supporting sentence 1 |
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| LIF | leukaemia inhibitory factor | neurotrophic/neuroprotective | PMID:9189906 |
Supporting sentence 1 |
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| CTF1 | Cardiotrophin 1 | neurotrophic/neuroprotective | PMID:17178916 |
Supporting sentence 1 |
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| OSM | oncostatin M | neurotrophic/neuroprotective | PMID:17023520 PMID:24996996 |
PMID:26311783 PMID:17023520 PMID:24996996 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
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| NRG1 | neuregulin 1 | neurotrophic/neuroprotective | PMID:18410912 PMID:22186019 |
Supporting sentence 1 Supporting sentence 2 |
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| BMP7 | Bone Morphogenetic Protein 7 | neurotrophic/neuroprotective | PMID:19765637 PMID:22461901 |
PMID:15126117 |
Supporting sentence 1 Supporting sentence 2 |
Supporting sentence 1 |
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| IGF2 | insulin like growth factor 2 | neurotrophic/neuroprotective | PMID:28575743 PMID:23497056 |
Supporting sentence 1 Supporting sentence 2 |
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| LEP | leptin | neurotrophic/neuroprotective | DOI:10.1093/cercor/bhw272 |
DOI:10.1038/cddis.2011.125 |
Supporting sentence 1 |
Supporting sentence 1 |
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| BMP2 | Bone Morphogenetic Protein 2 | neurotrophic/neuroprotective | PMID:24686133 |
Supporting sentence 1 |
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| BMP4 | Bone Morphogenetic Protein 4 | neurotrophic/neuroprotective | PMID:15555930 DOI:10.1111/jnc.14281 |
Supporting sentence 1 Supporting sentence 2 |
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| STIP1 | Stress Induced Phosphoprotein 1 | neurotrophic/neuroprotective | DOI:10.1111/jnc.14281 |
Supporting sentence 1 |
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| BMP6 | Bone Morphogenetic Protein 6 | neurotrophic/neuroprotective | PMID:11546913 PMID:24903778 PMID:17628512 |
PMID:11546913 |
Supporting sentence 1 Supporting sentence 2 Supporting sentence 3 |
Supporting sentence 1 |
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| CSF1 | Colony Stimulating Factor 3 | neurotrophic/neuroprotective | PMID:18602391 PMID:25468272 |
Supporting sentence 1 Supporting sentence 2 |
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| SNX1 | Sorting Nexin 1 | neurotrophic | DOI:10.1111/jnc.12524 |
Supporting sentence 1 |
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| PSD | Pleckstrin And Sec7 Domain Containing | neurotrophic | DOI:10.1111/jnc.12524 |
Supporting sentence 1 |
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| SERPINF1 | Serpin Family F Member 1 | neurotrophic/neuroprotective | PMID:19442875 |
Supporting sentence 1 |
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| NTRK2 | neurotrophic receptor tyrosine kinase 2 | neurotrophic | DOI:10.1038/celldisc.2016.30 |
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| CNTF | Ciliary Neurotrophic Factor | neurotrophic/neuroprotective | PMID:15555930 |
PMID:25896245 |
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| FGF2 | fibroblast growth factor 2 | neurotrophic/neuroprotective | PMID:16326808 PMID:19782732 PMID:10996460 PMID:9469637 PMID:9202296 |
DOI:10.1155/2017/2923182 PMID:26642808 PMID:17064673 |
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| FGF19 | fibroblast growth factor 19 | neurotrophic/neuroprotective | DOI:10.1167/iovs.07-1272 PMID:18385093 |
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| FGF8 | fibroblast growth factor 8 | neurotrophic/neuroprotective | PMID:10350562 DOI:10.1001/archneur.65.6.753 DOI:10.1016/S0006-8993(01)02726-3 PMID:25259688 |
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| FGF21 | fibroblast growth factor 21 | neurotrophic/neuroprotective | PMID:24468826 |
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| FGF13 | fibroblast growth factor 13 | neurotrophic | PMID:28922963 |
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| TGFB1 | Transforming growth factor-beta 1 | neurotrophic/neuroprotective | PMID:14526228 PMID:14514014 |
PMID:19327151 |
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| KL | Klotho | neurotrophic/neuroprotective | PMID:25037225 DOI:10.1111/jnc.13902 |
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| ZNF346 | Zinc Finger Protein 346 | neurotrophic/neuroprotective | DOI:10.1074/jbc.M114.597575 |
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| CHL1 | Cell Adhesion Molecule L1 Like | neurotrophic | PMID:15880726 |
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| L1CAM | L1 Cell Adhesion Molecule | neurotrophic | PMID:15880726 |
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| SSPO | SCO-Spondin | neurotrophic/neuroprotective | PMID:24667843 |
PMID:24667843 |
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| TIMP2 | TIMP metallopeptidase inhibitor 2 | no trophic/protective activity identified | ||||||
| TIMP4 | TIMP metallopeptidase inhibitor 4 | no trophic/protective activity identified | ||||||
| EPO | erythropoietin | neurotrophic/neuroprotective | PMID:28849166 PMID:30062636 PMID:26357589 PMID:25585642 |
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| TNFRSF1A | TNF receptor superfamily member 1A | no trophic/protective activity identified | ||||||
| TNFRSF18 | TNF receptor superfamily member 18 | no trophic/protective activity identified | ||||||
| TNFRSF1B | TNF receptor superfamily member 1B | no trophic/protective activity identified | ||||||
| BOK | BOK, BCL2 family apoptosis regulator | neurotrophic/neuroprotective | PMID:27098698 |
PMID:27098698 |
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| MTOR | mechanistic target of rapamycin kinase | neurotrophic/neuroprotective | ||||||
| ARG1 | arginase 1 | neurotrophic/neuroprotective | PMID:24655927 |
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| GBA | glucosylceramidase beta | neurotrophic/neuroprotective | PMID:26392287 |
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| GAL | galanin and GMAP prepropeptide | neurotrophic/neuroprotective | PMID:26764217 |
PMID:28203483 PMID:26764217 PMID:24726665 |
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| VIP | vasoactive intestinal peptide | neurotrophic/neuroprotective | PMID:25712659 |
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